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Identification and characterization of genes with specific expression in dendritic cells

URN to cite this document: urn:nbn:de:bvb:355-opus-2086

Heinz, Sven (2003) Identification and characterization of genes with specific expression in dendritic cells. PhD, Universität Regensburg

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Abstract (German)

Dendritische Zellen (DC) gehören neben Makrophagen und B-Lymphozyten zu den professionellen antigenpräsentierenden Zellen (APC) des Körpers. Bisher sind nur wenige DC-spezifisch exprimierte Markergene bekannt. Im Rahmen dieser Arbeit wurden über Repräsentationsdifferenzanalyse (RDA) der Expressionsprofile von aus Monozyten in vitro generierten DC versus Monozyten und parallel aus Monozyten ...

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Translation of the abstract (English)

To gain further insight into the differentiation pathways and lineage-commitment steps of dendritic cells (DCs) vs. macrophages as well as to define new molecular DC markers, genes with specific expression in DCs during differentiation from blood monocytes were identified by representational difference analysis (RDA). Subsequently, the expression pattern of the genes, namely DC-CK1, 15-LOX, ...

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Export bibliographical data



Item Type:Thesis of the University of Regensburg (PhD)
Date:8 July 2003
Referee:Prof. Dr. Armin Buschauer and PD Dr. S. W. Krause
Date of exam:18 July 2002
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Classification:
NotationType
molecular biologyNASA
immunologyNASA
Keywords:Dendritische Zelle , Monozyten-Makrophagen-System , Genexpression , Genregulation , MCP-4 , Hep27 (DHRS2) , Promotor , CpG-Methylierung , MCP-4 , Hep27 (DHRS2) , 15-Lipoxygenase , complement C1q C-chain , folate receptor beta
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Oct 2009 13:08
Last Modified:13 Mar 2014 11:15
Item ID:10104
Owner Only: item control page

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