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E-LDL and Ox-LDL differentially regulate ceramide and cholesterol raft microdomains in human Macrophages

Grandl, Margot and Bared, Salim Maa and Liebisch, Gerhard and Werner, Tobias and Barlage, Stefan and Schmitz, Gerd (2006) E-LDL and Ox-LDL differentially regulate ceramide and cholesterol raft microdomains in human Macrophages. Cytometry. Part A : the journal of the International Society for Analytical Cytology 69 (3), pp. 189-191.

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Other URL: http://dx.doi.org/10.1002/cyto.a.20232


Abstract

Atherosclerosis is characterized by the generation of lipid-loaded macrophage-derived foam cells. To study the effect of different types of atherogenic lipoproteins, human macrophages were loaded with enzymatically degraded low density lipoprotein (E-LDL) or oxidized LDL (Ox-LDL). Cellular cholesterol content was increased by E-LDL, whereas Ox-LDL increased the ceramide content. Cell surface ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
10.1002/cyto.a.20232DOI
16479605PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:01 Mar 2007
Last Modified:13 Mar 2014 09:44
Item ID:1022
Owner Only: item control page

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