Go to content
UR Home

Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro

Blank, Christian and Kuball, Juergen and Voelkl, Simon and Wiendl, Heinz and Becker, Bernd and Walter, Bernhard and Majdic, Otto and Gajewski, Thomas F and Theobald, Mathias and Andreesen, Reinhard and Mackensen, Andreas (2006) Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro. International journal of cancer. Journal international du cancer 119 (2), pp. 317-327.

Download (572kB) - Repository staff only

at PubMed

at publisher (via DOI)

Other URL: http://dx.doi.org/10.1002/ijc.21775


Human tumors frequently escape immune destruction, despite the presence of cytotoxic T cells (CTL) recognizing tumor-associated antigens (TAA). We have previously shown that programmed death ligand-1 (PD-L1), a recently identified ligand of the B7 superfamily, is expressed on murine tumors and can inhibit antitumor immune responses. To evaluate the clinical relevance of our animal model findings, ...


Export bibliographical data

Item Type:Article
Date:15 July 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
16482562PubMed ID
Keywords:RCC; PD-L1; PD-1; B7-H1; melanoma
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Deposited On:08 Feb 2007
Last Modified:13 Mar 2014 09:44
Item ID:1031
Owner Only: item control page


Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact person
Gernot Deinzer

Phone +49 941 943-2759