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New inhibitors of bacterial hyaluronidase - synthesis and structure-activity relationships

URN to cite this document: urn:nbn:de:bvb:355-opus-5856

Braun, Stephan (2006) New inhibitors of bacterial hyaluronidase - synthesis and structure-activity relationships. PhD, Universität Regensburg

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Abstract (English)

Potent and selective inhibitors of hyaluronidases are not reported in the literature so far. Such compounds are required as pharmacological tools to investigate the physiological and pathophysiological role of the enzymes and their preferred substrate, hyaluronic acid. Moreover, such inhibitors might be of therapeutic value, e.g. in the treatment of arthrosis, as new anti-fertility agents or as ...

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Translation of the abstract (German)

Potente, selektive Inhibitoren von Hyaluronidasen sind bislang nicht in der Literatur bechrieben. Solche Substanzen werden als pharmakologische Werkzeuge benötigt, um die (patho)physiologische Rolle der Hyaluronidasen und ihres Substrats, der Hyaluronsäure, zu untersuchen. Darüber hinaus könnten Hyaluronidase-Inhibitoren als Arzneistoffe interessant sein, z.B. zur Behandlung von Arthrosen, als ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:23 February 2006
Referee:Prof. Dr. Armin Buschauer
Date of exam:10 October 2005
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Keywords:Inhibitor , Hyaluronidasen , Struktur-Aktivitäts-Beziehung , Vitamin C-Derivate , Benzoxazol-2-thion , Inhibitor , hyaluronidase , Vitamin C derivatives , benzoxazole-2-thione
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Oct 2009 07:40
Last Modified:13 Mar 2014 11:34
Item ID:10385
Owner Only: item control page
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