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Drug delivery to the bone-implant interface: Functional hydroxyapatite surfaces and particles

URN to cite this document: urn:nbn:de:bvb:355-opus-7416

Schüssele, Andrea (2007) Drug delivery to the bone-implant interface: Functional hydroxyapatite surfaces and particles. PhD, Universität Regensburg

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Abstract (English)

With the goal of controlling the events at the bone-implant interface, it was the main objective of this thesis to provide a basis for the conjugation of cell stimulating molecules or targeting motifs to the surface of hydroxyapatite ceramic discs and particles. To this end, methods for surface functionalization have been investigated for the attachment of biomolecules. The approach focused on ...

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Translation of the abstract (German)

Um die Ereignisse an der Grenzfläche Knochen-Implantat zu kontrollieren, war es das Hauptziel dieser Arbeit, eine Basis für die Anbindung von zellstimulierenden Molekülen oder Targetingsequenzen an die Oberfläche von Hydroxylapatit-Keramikscheiben und Partikeln zu schaffen. Der gewählte Ansatz konzentrierte sich darauf, drei verlässliche und effiziente Prinzipien für die gesteigerte ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:9 May 2007
Referee:Achim (Prof. Dr.) Göpferich
Date of exam:2 November 2006
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:Hydroxylapatit , Knochen-Morphogenese-Proteine , Keramischer Werkstoff , Diphosphonate , Immobilisierung , Oberflächenmodifizierung , surface modification , bone morphogenetic protein , hydroxyapatite , ceramic , bisphosphonates
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Oct 2009 08:12
Last Modified:13 Mar 2014 11:44
Item ID:10511
Owner Only: item control page
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