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Potassium channels in prostate and colonic cancer

URN to cite this document: urn:nbn:de:bvb:355-opus-8563

Ousingsawat, Jiraporn (2007) Potassium channels in prostate and colonic cancer. PhD, Universität Regensburg

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Abstract (German)

Large conductance Ca2+-activated K+ channels in human prostate cancer The KCNMA1 gene encoding the alpha-subunit of BK channels is amplified and BK channel expression is enhanced in late-stage, metastatic and hormone-refractory human prostate cancer tissues, whereas benign prostate tissues show only a weak expression of BK channels. PC-3 hormone-insensitive prostate cancer cells, but not ...

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Translation of the abstract (German)

Ca2+- abhängige Kaliumkanäle (BK) in Prostatakarzinom KCNMA1 kodiert für die alpha-Untereinheit des großen Ca2+- abhängigen (BK) K+- Kanals und liegt in Spätstadien hormoninsensitive Prostatakarzinome in amplifizierter Form vor. Im Gegensatz hierzu zeigten gutartige Prostatagewebe eine nur schwache Expression von BK. Die Rolle von BK Kanälen für die Proliferation von Zellen des In PC-3 ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:11 October 2007
Referee:Rainer (PD Dr.) Schreiber
Date of exam:13 August 2007
Institutions:Biology, Preclinical Medicine > Institut für Physiologie
Keywords:Kaliumkanal , Dickdarmkrebs , Colonkrebs , Prostatakrebs , Proliferation , BK-Kanal , Genexpression , Carcinogenese , Histologie , , Potassium channel , colonic cancer
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Oct 2009 12:09
Last Modified:13 Mar 2014 11:48
Item ID:10592
Owner Only: item control page
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