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Isomer specific effects of conjugated linoleic acid on macrophage ABCG1 expression

URN to cite this document: urn:nbn:de:bvb:355-opus-8989

Ecker, Josef (2008) Isomer specific effects of conjugated linoleic acid on macrophage ABCG1 expression. PhD, Universität Regensburg.

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Abstract (English)

Conjugated linoleic acid (CLA) isomers are dietary fatty acids that modulate gene expression in many cell types. The aim of this work was to examine the function of the single c9,t11-, t10,c12- and t9,t11 CLA isomers on gene expression in human macrophages. Therefore, in vitro MCSF differentiated monocyte derived macrophages from three healthy donors and THP-1 macrophages were incubated with ...


Translation of the abstract (German)

Konjugierte Linolsäuren (CLAs) sind Positions- und geometrische Isomere der essentiellen Fettsäure Linolsäure und finden sich überwiegend in Rindfleisch und Milchprodukten. Ziel dieser Arbeit war es den Einfluß der einzelnen cis-9,trans-10-, trans-10,cis-12- und trans-9,trans-11-CLA Isomere auf die Genexpression von Makrophagen zu untersuchen. Dafür wurden in vitro mit MCSF (Macrophage Colony ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:13 July 2008
Referee:Thomas (PD Dr.) Langmann
Date of exam:27 November 2007
Institutions:Medicine > Lehrstuhl für Humangenetik
Biology, Preclinical Medicine
Keywords:Makrophage , Genexpression , Konjugierte Linolsäure , , macrophage , ABCG1 , CLA
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited on:27 Oct 2009 16:16
Last modified:13 Mar 2014 11:51
Item ID:10682
Owner only: item control page


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