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Association of single nucleotide polymorphisms in the LPA gene region with serum Lp(a) levels and myocardial infarction

URN to cite this document: urn:nbn:de:bvb:355-opus-10025

Neureuther, Katharina (2008) Association of single nucleotide polymorphisms in the LPA gene region with serum Lp(a) levels and myocardial infarction. PhD, Universität Regensburg

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Abstract (English)

Elevated serum Lp(a) levels are a risk factor for atherosclerosis and myocardial infarction. Lp(a) serum levels are highly heritable, and to a great extend determined by the LPA locus on chromosome 6q27. Polymorphisms influencing the Lp(a) levels have already been identified, but a proportion of the variance in Lp(a) levels remains to be explained. In this investigation different methods were ...

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Translation of the abstract (German)

Erhöhte Lp(a) Spiegel in Serum stellen einen Risikofaktor für Atherosklerose und Herzinfarkt dar. Der LPA Genlokus ist auf Chromosom 6q27 lokalisiert und bestimmt einen Grossteil der Lp(a) Serumspiegel, die sehr stark erblich sind. Es wurden bereits Polymorphismen identifiziert, die die Lp(a) Serumspiegel beeinflussen, aber ein Anteil der Varianz in den Lp(a) Spiegeln konnte noch nicht erklärt ...

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Item Type:Thesis of the University of Regensburg (PhD)
Date:13 July 2008
Referee:Thomas (PD Dr.) Langmann
Date of exam:0 July 2008
Institutions:Medicine > Lehrstuhl für Humangenetik
Biology, Preclinical Medicine
Keywords:Polymorphismus , Lipoprotein Lp(a) , Herzinfarkt , Epidemiologie , Genetik , SNP , , polymorphism , lipoprotein Lp(a) , myocardial infarction , epidemiology , genetics
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Oct 2009 16:28
Last Modified:13 Mar 2014 11:55
Item ID:10765
Owner Only: item control page

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