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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-109075
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.10907
Zusammenfassung
BACKGROUND: Computational enzyme design is far from being applicable for the general case. Due to computational complexity and limited knowledge of the structure-function interplay, heuristic methods have to be used. RESULTS: We have developed TransCent, a computational enzyme design method supporting the transfer of active sites from one enzyme to an alternative scaffold. In an optimization ...
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