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Fischer-344 rats are unsuitable for the MCAO filament model due to their cerebrovascular anatomy

Dittmar, Michael S. and Vatankhah, Bijan and Fehm, Nando P. and Schuierer, Gerhard and Bogdahn, Ulrich and Horn, Markus and Schlachetzki, Felix (2006) Fischer-344 rats are unsuitable for the MCAO filament model due to their cerebrovascular anatomy. Journal of neuroscience methods 156 (1-2), pp. 50-54.

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Other URL: http://dx.doi.org/10.1016/j.jneumeth.2006.02.003


Abstract

Middle cerebral artery occlusion (MCAO) in Fischer-344 rats results in a small variance of infarct size. However, complications are frequent especially in aged Fisher-344 rats undergoing endovascular suture occlusion of the middle cerebral artery. Analyzing our experiences with 165 Wistar, 13 Sprague-Dawley and 10 F-344 rats, we compared the incidence of impossible thread advancement and ...

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Item Type:Article
Date:30 September 2006
Institutions:Medicine > Lehrstuhl für Neurologie
Identification Number:
ValueType
10.1016/j.jneumeth.2006.02.003DOI
16530845PubMed ID
Keywords:Cerebral ischemia; Focal; Disease models; Animal; Rats; Middle cerebral artery occlusion; Carotid artery; Internal
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:02 Mar 2007
Last Modified:13 Mar 2014 09:45
Item ID:1104
Owner Only: item control page
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