Deutsch
Amslinger, S. and Hirsch, A. and Hampel, F. (2004) Synthesis of a biotinated amphiphile. Tetrahedron 60 (50), pp. 11565-11569.
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Abstract
The synthesis of a biotinated amphiphile assembled from D-(+)-biotin, ethylene diamine as spacer, galactaric acid and 1-dodecylamine was achieved in six steps. The key step was the synthesis of a bisacetonide protected galactaric ester, the structure of which was determined by X-ray analysis. Aminolysis, spacer attachment, coupling with biotin and deprotection led to the amphiphilic galactaramide. (C) 2004 Published by Elsevier Ltd.
| Item Type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Additional information (public): | Times Cited: 0 | ||||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Dr. Sabine Amslinger | ||||||
| Identification Number: |
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| Keywords: | D-(+)-biotin amphiphile galactaric acid carbohydrate derivatives Derivatives nmr | ||||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Yes | ||||||
| Owner: | Dr. Sabine Amslinger | ||||||
| Deposited On: | 24 Nov 2009 16:02 | ||||||
| Last Modified: | 07 Nov 2012 12:11 | ||||||
| Item ID: | 11063 |
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