Amslinger, S. and Hirsch, A. and Hampel, F. (2004) Synthesis of a biotinated amphiphile. Tetrahedron 60 (50), pp. 11565-11569.
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The synthesis of a biotinated amphiphile assembled from D-(+)-biotin, ethylene diamine as spacer, galactaric acid and 1-dodecylamine was achieved in six steps. The key step was the synthesis of a bisacetonide protected galactaric ester, the structure of which was determined by X-ray analysis. Aminolysis, spacer attachment, coupling with biotin and deprotection led to the amphiphilic ...
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|Additional information (public):||Times Cited: 0|
|Institutions:||Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Dr. Sabine Amslinger|
|Keywords:||D-(+)-biotin amphiphile galactaric acid carbohydrate derivatives Derivatives nmr|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Owner:||Dr. Sabine Amslinger|
|Deposited On:||24 Nov 2009 15:02|
|Last Modified:||07 Nov 2012 11:11|