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Enzyme-assisted preparation of isotope-labeled 1-deoxy-D-xylulose 5-phosphate

Hecht, S. and Kis, F. and Eisenreich, W. and Amslinger, S. and Wungsintaweekul, J. and Herz, S. and Rohdich, F. and Bacher, A. (2001) Enzyme-assisted preparation of isotope-labeled 1-deoxy-D-xylulose 5-phosphate. J. Org. Chem. 66 (11), pp. 3948-3952.

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Abstract

Recombinant l-deoxy-D-xylulose 5-phosphate synthase of Bacillus subtilis was used for the preparation of isotope-labeled 1-deoxy-D-xylulose 5-phosphate using isotope-labeled glucose and/ or isotope-labeled pyruvate as starting materials. The simple one-pot methods described afford almost every conceivable isotopomer of l-deoxy-rt-xylulose 5-phosphate carrying C-13 Or C-14 from commercially ...

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Item Type:Article
Date:2001
Additional information (public):Times Cited: 16
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Dr. Sabine Amslinger
Identification Number:
ValueType
ISI:000168911300039Web of Science ID
10.1021/jo0100300DOI
Keywords:Escherichia-coli biosynthesis precursor protein thiamin 4-diphosphocytidyl-2c-methyl-d-erythritol d-1-deoxyxylulose isoprenoids terpenoids catalyzes
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Dr. Sabine Amslinger
Deposited On:24 Nov 2009 14:24
Last Modified:13 Nov 2012 06:34
Item ID:11075
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