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Photoactivated coumaryl-diazopyruvate fluorescent label for amine functional groups of tissues containing type-I collagen

Timberlake, G. T. and Reddy, G. K. and Stehno-Bittel, L. and Weber, J. F. and Amslinger, S. and Givens, R. S. (2002) Photoactivated coumaryl-diazopyruvate fluorescent label for amine functional groups of tissues containing type-I collagen. Photochem. Photobiol. 76 (5), pp. 473-479.

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Abstract

The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because natural collagen crosslinks are formed between primary (1) amine groups of lysine ...

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Item Type:Article
Date:2002
Additional information (public):Times Cited: 2
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Dr. Sabine Amslinger
Identification Number:
ValueType
ISI:000179368700002Web of Science ID
10.1562/0031-8655(2002)0760473PCDFLF2.0.CO2DOI
Keywords:Connective-tissue cross-linking
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Dr. Sabine Amslinger
Deposited On:24 Nov 2009 14:36
Last Modified:12 Nov 2012 13:54
Item ID:11080
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