Gamulescu, Maria-Andreea and Chen, Youxin and He, Shikun and Spee, Christine and Jin, Manlin and Ryan, Stephen J. and Hinton, David R. (2006) Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor. Experimental eye research 83 (1), pp. 212-222.
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Other URL: http://dx.doi.org/10.1016/j.exer.2005.12.007
Retinal pigment epithelial (RPE) cells possess the potential to transdifferentiate into myofibroblasts after stimulation with transforming growth factor beta (TGFbeta) and are implicated in the pathogenesis of proliferative vitreoretinopathy. In this study we evaluated how TGFbeta2 and various extracellular matrix (ECM) proteins modulate the transdifferentiation of human fetal retinal pigment ...
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|Institutions:||Medicine > Lehrstuhl für Augenheilkunde|
|Keywords:||mesenchymal transdifferentiation; transforming growth factor; hepatocyte growth factor; extracellular matrix; fibronectin; alpha-smooth muscle actin|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||15 Mar 2007|
|Last Modified:||13 Mar 2014 09:45|