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Brave little world: spheroids as an in vitro model to study tumor-immune-cell interactions

Gottfried, Eva and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Kreutz, Marina (2006) Brave little world: spheroids as an in vitro model to study tumor-immune-cell interactions. Cell cycle (Georgetown, Tex.) 5 (7), pp. 691-695.

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Abstract

Multicellular tumor spheroids (MCTS) are a well-established 3-D in vitro model system that reflects the pathophysiological in vivo situation in tumor microregions and of avascular micrometastatic sites. Because monocytes and other immune cells infiltrate into MCTS of different origin, such spheroid cocultures are a valuable, still underestimated tool to systematically study heterologous ...

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Item Type:Article
Date:April 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
16582627PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:05 Mar 2007
Last Modified:20 Apr 2010 08:30
Item ID:1207
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