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Solid-phase synthesis of peptide - metal-complex conjugates

URN to cite this document: urn:nbn:de:bvb:355-opus-9026

Dirscherl, Georg (2009) Solid-phase synthesis of peptide - metal-complex conjugates. PhD, Universität Regensburg

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Abstract (English)

The synthesis of Fmoc protected SAAC and their use in solid-phase synthesis is reported. Peptide � metal complex conjugates were either obtained by incorporation of the metal coordinated SAAC followed by mild nucleophilic resin-cleavage or by complexation in metal salt solution after cleavage from the resin. The reported solid phase peptide synthesis protocols are suitable for automation and the ...

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Translation of the abstract (German)

Die Synthese von Fmoc geschützten Amino Säuren mit Chelatliganden und ihre Anwendung in der Festphasensynthese wird berichtet. Peptid � Metallkomplex Konjugate wurden entweder durch Inkorporation von Metall gebundenen, auf Amino Säure basierenden Chelatliganden erhalten, welche dann anschließend unter milden Bedingungen vom Resin abgespalten wurden. Alternativ konnten Peptid � Metallkomplex ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:6 January 2009
Referee:Burkhard (Prof. Dr.) König
Date of exam:14 December 2007
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:Metallkomplexe , Peptidsynthese , Festphasentechnik , Festphasensynthese , solid-phase peptide synthesis , metal-complex , single amino acid chelate
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Jan 2010 15:22
Last Modified:13 Mar 2014 12:26
Item ID:12078
Owner Only: item control page
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