Startseite UB

Guanidine-acylguanidine bioisosteric approach to address peptidergic receptors: pharmacological and diagnostic tools for the NPY Y1 receptor and versatile building blocks based on arginine substitutes

URN to cite this document: urn:nbn:de:bvb:355-opus-11116

Keller, Max (2009) Guanidine-acylguanidine bioisosteric approach to address peptidergic receptors: pharmacological and diagnostic tools for the NPY Y1 receptor and versatile building blocks based on arginine substitutes. PhD, Universität Regensburg

[img]
Preview
License: Publishing license for publications including print on demand
PDF
Download (7MB)

Abstract (English)

Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the central and peripheral nervous system. This 36-amino acid peptide is involved in the regulation of numerous physiological functions such as food intake, blood pressure, stress, nociception and hormone secretion. In humans, the action of NPY is mediated by four receptor subtypes (Y1, Y2, Y4 and Y5), members of the superfamily of ...

plus

Translation of the abstract (German)

Neuropeptid Y (NPY) ist eines der am häufigsten vorkommenden Neuropeptide im zentralen und peripheren Nervensystem. Das 36-Aminosäuren-Peptid ist an der Regulation einer Vielzahl physiologischer Funktionen wie z.B. Nahrungsaufnahme, Blutdruck, Hormonfreisetzung und Nozizeption beteiligt. NPY-Effekte werden beim Menschen von vier Rezeptorsubtypen (Y1, Y2, Y4, Y5), die zur Familie der G-Protein ...

plus


Export bibliographical data



Item Type:Thesis of the University of Regensburg (PhD)
Date:15 January 2009
Referee:Prof. Dr. Armin Buschauer
Date of exam:18 December 2008
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Keywords:Neuropeptid Y , Argininderivate , Isotopenmarkierung , Positronen-Emissions-Tomographie , Fluoreszenzspektroskopie , Bioisosterie , Acylgruppe , Y1-Rezeptorantagonist , Radioligand , Fluoreszenzligand , bivalenter Ligand , Argininamid BIBP 3226 , neuropeptide Y , Y1 receptor antagonist , labeled ligand , bivalent ligand , argininamide BIBP 3226
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Jan 2010 15:23
Last Modified:13 Mar 2014 12:26
Item ID:12092
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact