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Differentiation of hematopoietic progenitor cells towards the myeloid and B-lymphoid lineage by hepatocyte growth factor (HGF) and thrombopoietin (TPO) together with early acting cytokines

Grassinger, Jochen and Mueller, Gunnar and Zaiss, Matthias and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Hennemann, Burkhard (2006) Differentiation of hematopoietic progenitor cells towards the myeloid and B-lymphoid lineage by hepatocyte growth factor (HGF) and thrombopoietin (TPO) together with early acting cytokines. European Journal of Haematology 77 (2), pp. 134-144.

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Other URL: http://dx.doi.org/10.1111/j.1600-0609.2006.00673.x


Abstract

Objectives: The effect of stem cell factor (SCF), flt3-ligand (FL), and interleukin (IL)-3 (SF3) in combination with hepatocyte growth factor (HGF), thrombopoietin (TPO), and Hyper-IL-6 on maintenance and differentiation of early human peripheral blood-derived progenitor cells was investigated. Methods: Single sorted CD34(+) 38(-) cells were cultured with various combinations of these growth ...

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Item Type:Article
Date:26 April 2006
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
16650126PubMed ID
10.1111/j.1600-0609.2006.00673.xDOI
Keywords:CD34; differentiation; hematopoietic progenitor cells; hepatocyte growth factor; thrombopoietin; lymphopoiesis
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:23 Mar 2007
Last Modified:13 Mar 2014 09:47
Item ID:1230
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