Amino acid analysis in biological fluids by GC-MS

URN to cite this document: urn:nbn:de:bvb:355-opus-13168

Kaspar, Hannelore (2009) Amino acid analysis in biological fluids by GC-MS. PhD, Universität Regensburg

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Abstract (English)

Amino acids are intermediates in cellular metabolism and their quantitative analysis plays an important role in disease diagnostics. A gas chromatography-mass spectrometry (GC-MS) based method was developed for the quantitative analysis of free amino acids as their propyl chloroformate derivatives in biological fluids. Derivatization with propyl chloroformate could be carried out directly in the ...


Translation of the abstract (German)

Aminosäuren sind Zwischenprodukte im zellulären Stoffwechsel und ihre quantitative Analyse ist speziell bei der Diagnose von Krankheiten von enormer Bedeutung. Zur Bestimmung von Aminosäuren in unterschiedlichen biologischen Proben wurde eine gaschromatographische mit Massspektrometer gekoppelte Methode entwickelt, welche auf der Derivatisierung von Aminosäuren mit Chlorameisensäurepropylester ...


Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:6 August 2009
Referee:Peter (Prof. Dr.) Oefner
Date of exam:17 July 2009
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Instrumentelle Analytik (Prof. Frank-Michael Matysik)
Keywords:Metabolom , Aminosäuren , Massenspektrometrie , Harn , Chlorameisensäurederivate , Quantitative Analyse, GC-MS , , metabolomics , amino acids , gas chromatography mass spectrometry , urine , alkyl chloroformate
Subjects:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:18 Jan 2010 14:09
Last Modified:13 Mar 2014 12:38
Item ID:12318
Owner Only: item control page


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