Startseite UB

Mouse models targeted for the tissue inhibitor of metalloproteinases-3 (TIMP3) - molecular and functional dissection of Sorsby fundus dystrophy (SFD)

URN to cite this document: urn:nbn:de:bvb:355-epub-123907

Fogarasi, Marton (2010) Mouse models targeted for the tissue inhibitor of metalloproteinases-3 (TIMP3) - molecular and functional dissection of Sorsby fundus dystrophy (SFD). PhD, Universität Regensburg

[img]
Preview
License: Publishing license for publications including print on demand
PDF
Download (1MB)

Abstract (English)

Sorsby fundus dystrophy (SFD) is an autosomal dominant disorder of the central retina (Sorsby et al., 1949). It is characterized by subretinal neovascularization, atrophy of the retinal pigment epithelium and the choriocapillaris. It is a progressive disorder leading ultimately to blindness. Mutations in the TIMP3 molecule have been linked to SFD (Weber et al., 1994). So far, several point ...

plus

Translation of the abstract (German)

Sorsby Fundusdystrophie (SFD) ist eine autosomal dominante Erkrankung der zentralen Retina (Sorsby et al., 1949). Sie zeichnet sich durch subretinale Neovaskularisation, Atrophie des retinalen Pigmentepithels und der Choriokapillaris aus. Es ist eine Krankheit mit progressiven Verlauf, die letztendlich zu Blindhheit führt. Mutationen im TIMP3 Molekül werden mit SFD in Verbindung gebracht (Weber ...

plus


Export bibliographical data



Item Type:Thesis of the University of Regensburg (PhD)
Date:18 February 2010
Referee:Prof. Dr. Rainer Deutzmann and Prof. Dr. Bernhard Weber
Date of exam:3 December 2009
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Rainer Deutzmann
Keywords:TIMP-3, Matrix metalloproteinases, Sorsby fundus dystrophy, enzymatic inhibition
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:18 Feb 2010 15:13
Last Modified:13 Mar 2014 12:40
Item ID:12390
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact