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Acrylate and methacrylate esters: relationship of hemolytic activity and in vivo toxicity.

Dillingham, E. O. and Lawrence, W. H. and Autian, J. and Schmalz, Gottfried (1983) Acrylate and methacrylate esters: relationship of hemolytic activity and in vivo toxicity. Journal of biomedical materials research 17 (6), pp. 945-957.

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Abstract

Quantitative hemolysis assays of acrylate and methacrylate esters provided estimates of the intrinsic hemolytic activity (Hi, the slope of the concentration-response curve) and the concentrations effecting 5% (H5) and 50% (H50) hemolysis. The dependence of hemolytic activity and LD50 (mice) on physical properties (lipophilicity, molar refraction, and molecular volume) of the esters was determined ...

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Item Type:Article
Date:1983
Institutions:Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie
Identification Number:
ValueType
6654932PubMed ID
10.1002/jbm.820170606DOI
Classification:
NotationType
Acrylates/toxicityMESH
AnimalsMESH
Hemolysis/drug effectsMESH
Lethal Dose 50MESH
Methacrylates/toxicityMESH
MiceMESH
Mice, Inbred ICRMESH
Regression AnalysisMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:17 Feb 2010 15:22
Last Modified:13 Mar 2014 12:41
Item ID:12453
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