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CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis

Segerer, Stephan and Banas, Bernhard and Wörnle, Markus and Schmid, Holger and Cohen, Clemens D and Kretzler, Matthias and Mack, Matthias and Kiss, Eva and Nelson, Peter J and Schlöndorff, Detlef and Gröne, Hermann-Josef (2004) CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis. The American journal of pathology 164 (2), pp. 635-649.

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Chemokines play pivotal roles in the recruitment of inflammatory cells into the kidney. The chemokine receptors CXCR3 and CCR5 are expressed on activated T lymphocytes, and expression of CXCR3 by mesangial cells has been suggested. Detailed description of CXCR3 expression might form a rational basis for use as a diagnostic marker and for therapeutic CXCR3 targeting in human glomerulonephritis. We ...


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Item type:Article
Date:February 2004
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
14742268PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited on:14 Mar 2007
Last modified:13 Mar 2014 09:48
Item ID:1279
Owner only: item control page


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