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Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease

Pérez de Lema, Guillermo and Lucio-Cazaña, Francisco Javier and Molina, Ana and Luckow, Bruno and Schmid, Holger and de Wit, Cor and Moreno-Manzano, Victoria and Banas, Bernhard and Mampaso, Francisco and Schlöndorff, Detlef (2004) Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease. Kidney international 66 (3), pp. 1018-1028.

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Other URL: http://dx.doi.org/10.1111/j.1523-1755.2004.00850.x


Abstract

BACKGROUND: Retinoic acid (tRA) is an active metabolite of vitamin A with potent anti-inflammatory properties. We analyzed the effects of tRA on the development of lupus nephritis in MRL/lpr mice. METHODS: MRL/lpr mice received chow supplemented with vehicle or tRA (daily 10 mg/kg) from 8 to 14 weeks until their sacrifice. MRL/wt mice served as an additional control. RESULTS: tRA-treated MRL/lpr ...

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Item Type:Article
Date:September 2004
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
10.1111/j.1523-1755.2004.00850.xDOI
15327395PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:15 Mar 2007
Last Modified:13 Mar 2014 09:49
Item ID:1290
Owner Only: item control page

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