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Enhanced ecto-apyrase activity of stimulated endothelial or mesangial cells is downregulated by glucocorticoids in vitro

Kapojos, Jola J. and van den Berg, Anke and Borghuis, Theo and Banas, Bernhard and Huitema, Sippie and Poelstra, Klaas and Bakker, Winston W. (2004) Enhanced ecto-apyrase activity of stimulated endothelial or mesangial cells is downregulated by glucocorticoids in vitro. European journal of pharmacology 501 (1-3), pp. 191-198.

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Other URL: http://dx.doi.org/10.1016/j.ejphar.2004.08.008


Abstract

Endothelial as well as mesangial cells show enhanced activity of ecto-apyrase following pro-inflammatory stimulation in vitro. Since this ecto-enzyme appears to be able to regulate plasma hemopexin, which latter molecule plays a role in the pathogenesis of corticosteroid responsive nephrotic syndrome, the question was raised whether glucocorticoids are potentially able to downregulate ...

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Item Type:Article
Date:6 October 2004
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
15464078PubMed ID
10.1016/j.ejphar.2004.08.008DOI
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:15 Mar 2007
Last Modified:13 Mar 2014 09:49
Item ID:1291
Owner Only: item control page
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