Kapojos, Jola J. and van den Berg, Anke and Borghuis, Theo and Banas, Bernhard and Huitema, Sippie and Poelstra, Klaas and Bakker, Winston W. (2004) Enhanced ecto-apyrase activity of stimulated endothelial or mesangial cells is downregulated by glucocorticoids in vitro. European journal of pharmacology 501 (1-3), pp. 191-198.
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Endothelial as well as mesangial cells show enhanced activity of ecto-apyrase following pro-inflammatory stimulation in vitro. Since this ecto-enzyme appears to be able to regulate plasma hemopexin, which latter molecule plays a role in the pathogenesis of corticosteroid responsive nephrotic syndrome, the question was raised whether glucocorticoids are potentially able to downregulate ...
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|Date:||6 October 2004|
|Institutions:||Medicine > Lehrstuhl für Innere Medizin II|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||15 Mar 2007|
|Last Modified:||13 Mar 2014 09:49|