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Development of colloids for cell and tissue targeting: bisphosphonate-functionalized gold nanoparticles for the investigation of bone targeting

URN to cite this document: urn:nbn:de:bvb:355-epub-130940

Zayed, Gamal (2010) Development of colloids for cell and tissue targeting: bisphosphonate-functionalized gold nanoparticles for the investigation of bone targeting. PhD, Universität Regensburg

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Abstract (English)

Gold nanoparticles (GNPs) possess a great potential as model systems for the investigation of nanoparticulate drug delivery due to their ease of production, low toxicity and also the high stability of the noble metal in biological fluids. Due to their unique surface chemistry, they can be used as building platform for stable self assembled monolayers of thioalkylated poly(ethylene glycol)s with ...

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Translation of the abstract (German)

Goldnanopartikel (GNPs) haben ein großes Potential als Modellsysteme für die Untersuchung nanopartikulärer Arzneistofffreigabesysteme, nicht nur aufgrund ihrer einfachen Herstellung und niedrigen Toxizität, sondern auch aufgrund der hohen Stabilität des Edelmetalls Gold in biologischen Flüssigkeiten. Basierend auf der einzigartigen Oberflächenchemie des Goldes, können solche Partikel als ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:17 February 2010
Referee:Achim (Prof. Dr.) Göpferich
Date of exam:12 February 2009
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:Gold , Nanopartikel , Knochen , Diphosphonate , Polyethylenglykole , Targeted drug delivery , Nanokapsel , nanoparticles , bisphosphonate , PEG bone targeting
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:24 Feb 2010 09:14
Last Modified:13 Mar 2014 12:55
Item ID:13094
Owner Only: item control page
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