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Analysis of tissue-specific & allele-specific DNA methylation

URN to cite this document: urn:nbn:de:bvb:355-opus-13311

Schilling, Elmar (2010) Analysis of tissue-specific & allele-specific DNA methylation. PhD, Universität Regensburg

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Abstract (English)

Epigenetic mechanisms such as histone modifications and DNA methylation extend the information of the underlying genomic DNA sequence. Understanding cell type-specific epigenetic codes on a global level is a major challenge after the sequencing of the human genome has been completed. In addition, differences in epigenetic patterns between individuals may contribute to phenotypic variation and ...

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Translation of the abstract (German)

Epigenetik im Allgemeinen und DNA Methylierung im Speziellen, erweitern den Informationsgehalt der zugrundeliegenden genomischen DNA-Sequenz. Nachdem das menschliche Genom weitgehend sequenziert wurde, ist insbesondere das Verständnis von zelltypspezifischen epigenetischen Kodierungen in genomweiter Hinsicht die nächste zu bewältigende Herausforderung. Darüber hinaus sind unterschiedliche ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:4 February 2010
Referee:Michael (PD Dr.) Rehli
Date of exam:1 October 2009
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Keywords:Epigenetik , DNA , Methylierung , Gewebe , Allel , Epigenetik , DNA Methylierung , Methylierungsanalyse , Vererbung , zelltypspezifisch , allelespezifisch , DNA methylation , methylation profiling , inheritance , cell type-specific , allele-specific
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:24 Feb 2010 09:17
Last Modified:13 Mar 2014 12:56
Item ID:13101
Owner Only: item control page
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