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DNA methylation in chromatin - complexes and mechanisms

URN to cite this document: urn:nbn:de:bvb:355-epub-133861

Felle, Max (2010) DNA methylation in chromatin - complexes and mechanisms. PhD, Universität Regensburg

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Abstract (English)

The DNA in the eukaryotic genome is packaged into chromatin whose basic repeating unit is the nucleosome consisting of 147bp of DNA wrapped around an octameric histone core. The histone octamer is composed of two copies of each of the four histone proteins H2A, H2B, H3 and H4. DNA methylation is an epigenetic mechanism that is involved in various important processes in the cell such as ...

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Translation of the abstract (German)

Die DNA des eukaryotischen Genoms liegt in Form von Chromatin vor, dessen wiederholende Grundeinheit das Nukleosom dargestellt. Im Nukleosom ist die DNA (147bp) um ein Oktamer von basischen Proteinen, den vier Histon-Proteinen H2A, H2B, H3 und H4, gewickelt. Die DNA-Methylierung ist ein epigenetischer Mechanismus, der an verschiedenen, bedeutenden Prozesses in der Zelle, wie der Differenzierung, ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:4 August 2010
Referee:Prof. Dr. Gernot Längst
Date of exam:29 July 2009
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Research groups and research centres:Not selected
Keywords:DNS-Methyltransferase, Chromatin, Nucleosom, Plazenta, HeLa-Zelle, Ubiquitin-Protein-Ligase, Ubiquitin-spezifische-Protease, Dnmt1, Kernextrakt, Dnmt3a, Dnmt3b, DNA methylation, ubiquitin-specific-protease, ubiquitin-ligase, Dnmt1, Dnmt3
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:04 Aug 2010 11:12
Last Modified:13 Mar 2014 13:56
Item ID:13386
Owner Only: item control page
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