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Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins

Hagen, Ilja and Ecker, Margit and Lagorce, Arnaud and Francois, Jean M. and Sestak, Sergej and Rachel, Reinhard and Grossmann, Guido and Hauser, Nicole C. and Hoheisel, Jörg D. and Tanner, Widmar and Strahl, Sabine (2004) Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins. Molecular microbiology 52 (5), pp. 1413-1425.

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Abstract

The covalently linked cell wall protein Ccw12p of Saccharomyces cerevisiae is a GPI-anchored protein (V. Mrsa et al., 1999, J Bacteriol 181: 3076-3086). Although only 121 amino acids long, the haemagglutinin-tagged protein released by laminarinase from the cell wall possesses an apparent molecular mass of > 300 kDa. A membrane-bound form with an apparent molecular mass of 58 kDa is highly O- and ...

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Item Type:Article
Date:2004
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie > Prof. Dr. Michael Thomm
Identification Number:
ValueType
15165243PubMed ID
10.1111/j.1365-2958.2004.04064.xDOI
Classification:
NotationType
Cell Wall/ultrastructureMESH
Chitin/chemistryMESH
Gene Expression ProfilingMESH
Gene Expression Regulation, FungalMESH
Glycosylphosphatidylinositols/metabolismMESH
Membrane Glycoproteins/metabolismMESH
MutationMESH
Oligonucleotide Array Sequence AnalysisMESH
PhenotypeMESH
Protein Processing, Post-TranslationalMESH
Saccharomyces cerevisiae/ultrastructureMESH
Saccharomyces cerevisiae Proteins/metabolismMESH
Transcription, GeneticMESH
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:19 Mar 2010 09:57
Last Modified:19 Mar 2010 09:57
Item ID:13522
Owner Only: item control page
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