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Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli

Blumer, Caroline and Kleefeld, Alexandra and Lehnen, Daniela and Heintz, Margit and Dobrindt, Ulrich and Nagy, Gábor and Michaelis, Kai and Emödy, Levente and Polen, Tino and Rachel, Reinhard and Wendisch, Volker F. and Unden, Gottfried (2005) Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli. Microbiology 151 (10), pp. 3287-3298.

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Abstract

Type 1 fimbriae of Escherichia coli facilitate attachment to the host mucosa and promote biofilm formation on abiotic surfaces. The transcriptional regulator LrhA, which is known as a repressor of flagellar, motility and chemotaxis genes, regulates biofilm formation and expression of type 1 fimbriae. Whole-genome expression profiling revealed that inactivation of lrhA results in an increased ...

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Item Type:Article
Date:2005
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie > Prof. Dr. Michael Thomm
Identification Number:
ValueType
16207912PubMed ID
10.1099/mic.0.28098-0DOI
Classification:
NotationType
AnimalsMESH
Bacterial AdhesionMESH
Biofilms/growth & developmentMESH
Escherichia coli/pathogenicityMESH
Escherichia coli Infections/mortalityMESH
Escherichia coli Proteins/metabolismMESH
Fimbriae, Bacterial/metabolismMESH
Gene Expression ProfilingMESH
Gene Expression Regulation, BacterialMESH
HumansMESH
MiceMESH
MutationMESH
Oligonucleotide Array Sequence AnalysisMESH
Promoter Regions, GeneticMESH
Transcription Factors/metabolismMESH
Urinary Tract Infections/mortalityMESH
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:19 Mar 2010 09:48
Last Modified:19 Mar 2010 09:48
Item ID:13541
Owner Only: item control page
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