Startseite UB

Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release

Schlee, Sandra and Deuss, Miriam and Bruning, Marc and Ivens, Andreas and Schwab, Thomas and Hellmann, Nadja and Mayans, Olga and Sterner, Reinhard (2009) Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release. Biochemistry 48 (23), pp. 5199-209.

Full text not available from this repository.

at PubMed

at publisher (via DOI)


Abstract

Anthranilate phosphoribosyltransferase from the hyperthermophilic archaeon Sulfolobus solfataricus (ssAnPRT) is encoded by the sstrpD gene and catalyzes the reaction of anthranilate (AA) with a complex of Mg(2+) and 5'-phosphoribosyl-alpha1-pyrophosphate (Mg.PRPP) to N-(5'-phosphoribosyl)-anthranilate (PRA) and pyrophosphate (PP(i)) within tryptophan biosynthesis. The ssAnPRT enzyme is highly ...

plus


Export bibliographical data

Item Type:Article
Date:2009
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Identification Number:
ValueType
19385665PubMed ID
10.1021/bi802335sDOI
Classification:
NotationType
Anthranilate Phosphoribosyltransferase/metabolismMESH
CatalysisMESH
Crystallography, X-RayMESH
Escherichia coli/metabolismMESH
KineticsMESH
Magnesium/pharmacologyMESH
Models, MolecularMESH
Protein ConformationMESH
Recombinant Proteins/metabolismMESH
Sulfolobus solfataricus/metabolismMESH
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Gernot Deinzer
Deposited On:19 Mar 2010 11:10
Last Modified:19 Mar 2010 11:11
Item ID:13648
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact