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Recognition of peptide and protein phosphorylation and inhibition of melanoma inhibitory activity (MIA) protein

URN to cite this document: urn:nbn:de:bvb:355-epub-136538

Riechers, Alexander (2011) Recognition of peptide and protein phosphorylation and inhibition of melanoma inhibitory activity (MIA) protein. PhD, Universität Regensburg.

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Abstract (English)

The first part of this thesis describes the use of artificial metal chelate receptors for the recognition of phosphorylated peptides and proteins. Ditopic receptors were used for the differentiation of phosphorylated peptides in solution. After observing binding of a bis-Zn(II)-cyclen triazine to phosphorylated amino acids in a peptide in this project, new receptors were synthesized with the ...


Translation of the abstract (German)

Der erste Teil dieser Arbeit beschreibt die Verwendung von bis-Zn(II)-Cyclen Triazin Komplexen zur molekularen Erkennung von phosphorylierten Peptiden und Proteinen. Rezeptoren mit zwei Bindungsstellen wurden verwendet um phosphorylierte Peptide in Lösung zu unterscheiden. Ausgehend von diesen Ergebnissen wurden Fluoreszenz-markierte Metall Chelate zur Detektion von phosphorylierten Proteinen in ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:4 May 2011
Referee:Prof. Dr. Burkhard König and Prof. Dr. Anja Katrin Bosserhoff and Prof. Dr. Otto Wolfbeis
Date of exam:4 May 2010
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:Phosphorylation, fluorescence spectroscopy, malignant melanoma, melanoma inhibitory activity (MIA) protein, CD-RAP
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited on:04 May 2011 09:14
Last modified:13 Mar 2014 17:18
Item ID:13653
Owner only: item control page


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