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Destruction of human solid tumors by alkyl lysophospholipids

Runge, M. H. and Andreesen, Reinhard and Pfleiderer, A. and Munder, P. G. (1980) Destruction of human solid tumors by alkyl lysophospholipids. Journal of the National Cancer Institute 64 (6), pp. 1301-6.

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Abstract

Alkyl lysophospholipids (ALP) are synthetic analogs of the naturally occurring 2-lysophosphatidylcholine. The effect of ALP on the proliferation of 22 different gynecologic malignant tumors in humans was studied in vitro. ALP caused progressive death of tumor cells over 24-96 hours. In addition, tumor specimens from the tested human tumors were xenotransplanted into NMRI nude mice. ALP induced a ...

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Item Type:Article
Date:1980
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
6929370PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
AnimalsMESH
Carcinoma/drug therapyMESH
FemaleMESH
Genital Neoplasms, Female/drug therapyMESH
HumansMESH
Lysophosphatidylcholines/therapeutic useMESH
LysophospholipidsMESH
MiceMESH
Mice, NudeMESH
Neoplasm TransplantationMESH
Neoplasms, Experimental/drug therapyMESH
Ovarian Neoplasms/drug therapyMESH
Phospholipids/therapeutic useMESH
Sarcoma/drug therapyMESH
Teratoma/drug therapyMESH
Transplantation, HeterologousMESH
Uterine Cervical Neoplasms/drug therapyMESH
Uterine Neoplasms/drug therapyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:13
Last Modified:13 Apr 2010 05:13
Item ID:14167
Owner Only: item control page
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