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Differentielle Regulation des Androgenrezeptor-Promoters in hormonsensitiven und resistenten Prostatakarzinomzellen

Kopp, H. and Masters, J. R. and Wieland, W. and Hofstädter, Ferdinand and Buettner, R. (1993) Differentielle Regulation des Androgenrezeptor-Promoters in hormonsensitiven und resistenten Prostatakarzinomzellen. Verhandlungen der Deutschen Gesellschaft für Pathologie 77, pp. 129-32.

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Abstract

The sensitivity of prostate epithelial cells to androgens is mediated by the androgen receptor (AR). Analyses of cell lines in vitro and prostate carcinomas in vivo provide evidence that loss of AR expression parallels the loss of sensitivity to androgens. The aim of our work is to analyze the genetic control elements of the AR gene and answer the question of why these elements fail to function ...

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Item Type:Article
Date:1993
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
7511270PubMed ID
Classification:
NotationType
Androgens/pharmacologyMESH
Cell LineMESH
Enhancer Elements, GeneticMESH
Gene Expression Regulation, NeoplasticMESH
HumansMESH
Promoter Regions, GeneticMESH
Receptors, Androgen/geneticsMESH
Restriction MappingMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:14 Apr 2010 08:32
Last Modified:14 Apr 2010 08:32
Item ID:14172
Owner Only: item control page
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