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Cytotoxic activity in the serum of a patient with metastasizing nephroblastoma given intravenous infusions of alkyl-lysophospholipids in a phase I study

Andreesen, Reinhard and Arnold, H. and Löhr, G. W. (1982) Cytotoxic activity in the serum of a patient with metastasizing nephroblastoma given intravenous infusions of alkyl-lysophospholipids in a phase I study. Blut 44 (2), pp. 79-82.

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Abstract

In a phase I study a cytotoxic activity in the serum of a tumor patient given infusions of synthetic alkyl-lysophospholipid has been demonstrated. Serum samples collected after ALP infusions inhibited 3H-thymidine incorporation by human leukemic cells to an extent that correlated to the dose of ALP administered. Serum taken after the highest dose of ALP given (50 mg/kg body weight) led to ...

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Item Type:Article
Date:1982
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
6277413PubMed ID
Classification:
NotationType
AdultMESH
HumansMESH
Injections, IntravenousMESH
Kidney Neoplasms/drug therapyMESH
LysophospholipidsMESH
MaleMESH
Neoplasm MetastasisMESH
Phospholipids/therapeutic useMESH
Wilms Tumor/drug therapyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:11
Last Modified:13 Apr 2010 05:11
Item ID:14175
Owner Only: item control page
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