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Cell-destructive activity in the serum of a tumor patient after infusion of alkyl lysophospholipid

Andreesen, Reinhard and Munder, P. G. (1983) Cell-destructive activity in the serum of a tumor patient after infusion of alkyl lysophospholipid. Journal of the National Cancer Institute 70 (4), pp. 623-7.

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Abstract

Sera collected from 1 tumor patient after a 12-hour infusion of 30-50 mg alkyl lysophospholipids (ALP)/kg induced a progressive destruction of human leukemia cells (HL60) in vitro. This cytotoxic serum activity correlated with the dose of ALP administered and was inhibited by the addition of a metabolizable lysophospholipid analogue. Human bone marrow cells and concanavalin A-stimulated ...

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Item Type:Article
Date:1983
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
6300501PubMed ID
Classification:
NotationType
AdultMESH
Antineoplastic Agents/therapeutic useMESH
Cell LineMESH
Cell Survival/drug effectsMESH
HumansMESH
Kidney Neoplasms/bloodMESH
Leukemia, Myeloid, Acute/physiopathologyMESH
LysophospholipidsMESH
MaleMESH
Phospholipids/toxicityMESH
Wilms Tumor/bloodMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:10
Last Modified:13 Apr 2010 05:10
Item ID:14177
Owner Only: item control page
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