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Studies on various parameters influencing leukemic cell destruction by alkyl-lysophospholipids

Andreesen, Reinhard and Modolell, M. and Oepke, G. H. and Common, H. and Löhr, G. W. and Munder, P. G. (1982) Studies on various parameters influencing leukemic cell destruction by alkyl-lysophospholipids. Anticancer research 2 (1-2), pp. 95-100.

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Abstract

Critical parameters of alkyl-lysophospholipid (ALP) induced destruction of freshly isolated human leukemic cells have been evaluated. The destructive activity of ALP is shown to be competitively inhibited by metabolizable lysophospholipids added to the cultures. It has also been found that destruction depends on the amount of serum present. Temperature and Ph strongly influence the cytotoxic ...

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Item Type:Article
Date:1982
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
7114806PubMed ID
Classification:
NotationType
Acute DiseaseMESH
Antineoplastic Agents/therapeutic useMESH
Cells, CulturedMESH
Cholesterol/pharmacologyMESH
Dexamethasone/pharmacologyMESH
Drug SynergismMESH
HumansMESH
Hydrogen-Ion ConcentrationMESH
Leukemia/drug therapyMESH
Lysophosphatidylcholines/therapeutic useMESH
LysophospholipidsMESH
Phospholipids/therapeutic useMESH
Prednisolone/pharmacologyMESH
TemperatureMESH
Vinca Alkaloids/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:07
Last Modified:13 Apr 2010 05:07
Item ID:14192
Owner Only: item control page
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