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Human macrophage maturation and heterogeneity: analysis with a newly generated set of monoclonal antibodies to differentiation antigens

Andreesen, Reinhard and Bross, K. J. and Osterholz, J. and Emmrich, F. (1986) Human macrophage maturation and heterogeneity: analysis with a newly generated set of monoclonal antibodies to differentiation antigens. Blood 67 (5), pp. 1257-64.

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Abstract

We have analyzed the expression of late differentiation antigens during terminal in vitro maturation of human macrophages (M phi) from blood monocytes (MO) in comparison to their distribution among mature M phi residing in various tissue sites. By immunizing mice with M phi derived from blood MO by culture on hydrophobic Teflon foils, monoclonal antibodies (mAbs) were developed (MAX.1, MAX.2, ...

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Item Type:Article
Date:1986
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
3008886PubMed ID
Classification:
NotationType
AnimalsMESH
Antibodies, MonoclonalMESH
Antigens, Surface/analysisMESH
Blood Platelets/immunologyMESH
Cell DifferentiationMESH
Cross ReactionsMESH
HumansMESH
Immunoenzyme TechniquesMESH
Macrophages/immunologyMESH
Megakaryocytes/immunologyMESH
MiceMESH
Mice, Inbred BALB CMESH
Receptors, Cell Surface/immunologyMESH
Receptors, TransferrinMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:02
Last Modified:13 Apr 2010 05:02
Item ID:14202
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