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Human macrophage maturation in vitro: expression of functional transferrin binding sites of high affinity

Andreesen, Reinhard and Sephton, R. G. and Gadd, S. and Atkins, R. C. and De Abrew, S. (1988) Human macrophage maturation in vitro: expression of functional transferrin binding sites of high affinity. Blut 57 (2), pp. 77-83.

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Abstract

Human blood monocytes (mo) when cultured in suspension on hydrophobic teflon membranes undergo terminal maturation to macrophages (MO). Together with the appearance of new lineage-restricted differentiation antigens, mature MO but not blood mo, express transferrin (TF) receptor molecules as detected by immunostaining methods. Here we report that radio- and fluorescein-labelled TF binds to a ...

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Item Type:Article
Date:1988
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
3408816PubMed ID
Classification:
NotationType
Cell DivisionMESH
Gallium Radioisotopes/diagnostic useMESH
HumansMESH
Iron Radioisotopes/diagnostic useMESH
Macrophages/ultrastructureMESH
Protein BindingMESH
Receptors, Transferrin/physiologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:43
Last Modified:14 Apr 2010 05:43
Item ID:14246
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