von Briesen, H. and Andreesen, Reinhard and Esser, R. and Brugger, W. and Meichsner, C. and Becker, K. and Rübsamen-Waigmann, H. (1990) Infection of monocytes/macrophages by HIV in vitro. Research in virology 141 (2), pp. 225-31.
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Because of the very important role of the mononuclear phagocyte system in the immunopathogenesis of HIV infection, a culture system for in vitro studies of infection of monocytes/macrophages with HIV was developed. A method is described for the infection of human monocytes/macrophages cultured on hydrophobic membranes (Teflon) with different strains of HIV. The HIV isolates can be characterized according to their replication potential on monocytes/macrophages cultures. The biological properties of some HIV1 and HIV2 isolates are compared in lymphocyte and monocyte/macrophage cultures.
|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||14 Apr 2010 05:33|
|Last Modified:||14 Apr 2010 05:33|