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Mitoxantrone/high-dose Ara-C and recombinant human GM-CSF in the treatment of refractory non-Hodgkin's lymphoma. A pilot study

Ho, A. D. and Del Valle, F. and Engelhard, M. and Hiddemann, W. and Rückle, H. and Schlimok, G. and Haas, R. and Thiel, E. and Andreesen, Reinhard and Fiedler, W. (1990) Mitoxantrone/high-dose Ara-C and recombinant human GM-CSF in the treatment of refractory non-Hodgkin's lymphoma. A pilot study. Cancer 66 (3), pp. 423-30.

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Abstract

Previous study has shown that the combination of mitoxantrone (Novantrone, NO) and Ara-C (AC) (NOAC) was active in refractory non-Hodgkin's lymphoma (NHL) but myelosuppression was dose-limiting. In a pilot study, we investigated the effects of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) after NOAC chemotherapy in patients with refractory NHL. NO was applied at a ...

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Item Type:Article
Date:1990
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
2194641PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Colony-Stimulating Factors/adverse effectsMESH
Cytarabine/administration & dosageMESH
Drug Administration ScheduleMESH
FemaleMESH
Granulocyte-Macrophage Colony-Stimulating FactorMESH
Growth Substances/adverse effectsMESH
HumansMESH
Lymphoma, Non-Hodgkin/mortalityMESH
MaleMESH
Middle AgedMESH
Mitoxantrone/administration & dosageMESH
Multicenter Studies as TopicMESH
Pilot ProjectsMESH
Recombinant Proteins/adverse effectsMESH
Remission InductionMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:30
Last Modified:14 Apr 2010 05:30
Item ID:14260
Owner Only: item control page
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