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Sequential studies on the role of mitoxantrone, high-dose cytarabine, and recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of refractory non-Hodgkin's lymphoma

Ho, A. D. and Del Valle, F. and Haas, R. and Engelhard, M. and Hiddemann, W. and Rückle, H. and Schlimok, G. and Thiel, E. and Andreesen, Reinhard and Fiedler, W. (1990) Sequential studies on the role of mitoxantrone, high-dose cytarabine, and recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of refractory non-Hodgkin's lymphoma. Seminars in oncology 17 (6 Suppl 10), 14-8; discussion 18.

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Abstract

Mitoxantrone (Novantrone, American Cyanamid Company; NO) and high-dose cytarabine (Ara-C; AC) have each been shown to be active in non-Hodgkin's lymphomas (NHL) in various studies. The studies reported here are sequential. The first study (NOAC I) combined high-dose cytarabine (3 g/m2/12 h as a 3 h infusion on day 1) with mitoxantrone (10 mg/m2/d on days 2 and 3). Of 31 patients with relapsed and ...

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Item Type:Article
Date:1990
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
2259918PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Cytarabine/administration & dosageMESH
Drug Administration ScheduleMESH
Drug ResistanceMESH
FemaleMESH
Granulocyte-Macrophage Colony-Stimulating Factor/administration & dosageMESH
HumansMESH
Lymphoma, Non-Hodgkin/pathologyMESH
MaleMESH
Middle AgedMESH
Mitoxantrone/administration & dosageMESH
Neoplasm StagingMESH
Recombinant Proteins/administration & dosageMESH
Remission InductionMESH
Survival RateMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:30
Last Modified:14 Apr 2010 05:30
Item ID:14261
Owner Only: item control page
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