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Large-scale production of human tumorcytotoxic macrophages grown from blood monocytes of cancer patients

Brugger, W. and Scheibenbogen, C. and Krause, S. and Andreesen, Reinhard (1991) Large-scale production of human tumorcytotoxic macrophages grown from blood monocytes of cancer patients. Cancer detection and prevention 15 (5), pp. 407-12.

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Abstract

For adoptive immunotherapy protocols using cells of the macrophage (M phi) system, well differentiated and functionally competent effector cells are required. In this presentation the generation of a large number of M phi grown in vitro from blood monocytes (mo) is reported. Mononuclear cells (MNC) were collected by cytapheresis and subsequent Ficoll centrifugation. Mean yield was 6.9 x 10(9) MNC ...

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Item Type:Article
Date:1991
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
1751952PubMed ID
Classification:
NotationType
AdultMESH
Antigens, Differentiation/analysisMESH
Cell CountMESH
Cell DifferentiationMESH
Cells, CulturedMESH
Culture Techniques/methodsMESH
CytapheresisMESH
Cytotoxicity Tests, ImmunologicMESH
Endotoxins/pharmacologyMESH
FemaleMESH
Granulocyte-Macrophage Colony-Stimulating Factor/secretionMESH
HumansMESH
Immunotherapy, AdoptiveMESH
Interferon-gamma, Recombinant/pharmacologyMESH
Interleukin-6/secretionMESH
Macrophage ActivationMESH
Macrophages/secretionMESH
MaleMESH
Middle AgedMESH
MonocytesMESH
Neoplasms/therapyMESH
Transplantation, AutologousMESH
Tumor Necrosis Factor-alpha/secretionMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:26
Last Modified:14 Apr 2010 05:26
Item ID:14267
Owner Only: item control page
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