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The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta chains (p55 and p75)

Scheibenbogen, C. and Keilholz, U. and Richter, M. and Andreesen, Reinhard and Hunstein, W. (1992) The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta chains (p55 and p75). Research in immunology 143 (1), pp. 33-7.

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Abstract

Human monocytes constitutively express the intermediate-affinity interleukin-2 receptor (IL2R) p75, while freshly isolated monocytes lack the low-affinity IL2R p55 (Tac antigen, CD25). Lipopolysaccharide (LPS) upregulates expression of p75 and effectively induces surface expression of CD25 on human monocytes within 18 h, as detected by two-colour FACS analysis on 59.5 +/- 7.6% of cells. ...

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Item Type:Article
Date:1992
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
1565844PubMed ID
Classification:
NotationType
HumansMESH
Macrophage ActivationMESH
Macrophages/immunologyMESH
Molecular WeightMESH
Monocytes/immunologyMESH
Protein ConformationMESH
Receptors, Interleukin-2/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:19
Last Modified:14 Apr 2010 05:19
Item ID:14279
Owner Only: item control page
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