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Interferon-gamma-induced expression of tissue factor activity during human monocyte to macrophage maturation

Scheibenbogen, C. and Moser, H. and Krause, S. and Andreesen, Reinhard (1992) Interferon-gamma-induced expression of tissue factor activity during human monocyte to macrophage maturation. Haemostasis 22 (4), pp. 173-8.

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Abstract

The expression of tissue factor (TF) during differentiation of human monocytes (MO) to macrophages (MAC) in vitro is investigated in this study. In MO, TF activity can be induced by the addition of lipopolysaccharides (LPS) as detected by Northern blot analysis and measured functionally as procoagulant activity (PCA), while IFN gamma alone has only marginal stimulatory activity. During in vitro ...

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Item Type:Article
Date:1992
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
1468719PubMed ID
Classification:
NotationType
Blood Coagulation Factors/biosynthesisMESH
Cell AdhesionMESH
Cell Differentiation/drug effectsMESH
Cells, CulturedMESH
Gene Expression Regulation/drug effectsMESH
HumansMESH
Interferon-gamma/pharmacologyMESH
Lipopolysaccharides/pharmacologyMESH
Macrophages/drug effectsMESH
Monocytes/drug effectsMESH
PolytetrafluoroethyleneMESH
Thromboplastin/biosynthesisMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:17
Last Modified:14 Apr 2010 05:17
Item ID:14280
Owner Only: item control page
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