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1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages

Kreutz, Marina and Andreesen, Reinhard and Krause, S. W. and Szabo, A. and Ritz, E. and Reichel, H. (1993) 1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. Blood 82 (4), pp. 1300-1307.

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Abstract

It has been well established that human mononuclear phagocytes have the capacity to produce 1,25-dihydroxy-vitamin D3 [1,25(OH)3D3] and express the vitamin D receptor (VDR). However, 1 alpha-hydroxylase activity and VDR receptor expression during differentiation of monocytes (MO) into mature macrophages (MAC) have not been previously examined. The in vitro maturation of blood MO can serve as a ...

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Item Type:Article
Date:1993
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
8394753PubMed ID
Classification:
NotationType
24,25-Dihydroxyvitamin D 3/metabolismMESH
Calcifediol/metabolismMESH
Calcitriol/biosynthesisMESH
Cell DifferentiationMESH
Cells, CulturedMESH
HumansMESH
Macrophages/metabolismMESH
Monocytes/metabolismMESH
RNA, Messenger/analysisMESH
Receptors, CalcitriolMESH
Receptors, Steroid/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:12
Last Modified:13 Mar 2014 18:00
Item ID:14283
Owner Only: item control page

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