Reichle, A. and Diddens, H. and Altmayr, F. and Rastetter, J. and Andreesen, Reinhard (1994) Chemomodulation of drugs involved in multidrug resistance in chronic lymphatic leukemia of the B-cell type. Cancer chemotherapy and pharmacology 34 (4), pp. 307-16.
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Reduced drug accumulation may be one reason for intrinsic drug resistance in chronic lymphatic leukemia of the B-cell type (B-CLL). Immunophenotyped leukemic human B-cells from 38 cases of B-CLL were characterized for P-glycoprotein (PGP) content. In all, 30 cases of B-CLL were additionally analyzed for further parameters: accumulation of daunorubicin (DNR, n = 20) and rhodamine 123 (Rh123, n = ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||14 Apr 2010 05:08|
|Last Modified:||14 Apr 2010 05:08|