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111In-oxine labelling of tumour-cytotoxic macrophages generated in vitro from circulating blood monocytes: an in vitro evaluation

Marienhagen, J. and Hennemann, B. and Andreesen, Reinhard and Eilles, C. (1995) 111In-oxine labelling of tumour-cytotoxic macrophages generated in vitro from circulating blood monocytes: an in vitro evaluation. Nuclear medicine communications 16 (5), pp. 357-61.

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Abstract

The labelling of ex-vivo activated macrophages with doses of 111In-oxine sufficient for gamma camera imaging does not damage cell viability or the functional competence of cells (secretion of tumour necrosis factor-alpha and interleukin-6). The mean labelling efficiency was about 84%. Release of 111In equivalent to 15% occurred over 24 h under cell culture conditions, indicating good stability of ...

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Item Type:Article
Date:1995
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
7659388PubMed ID
Classification:
NotationType
Cell SurvivalMESH
Cytotoxicity, ImmunologicMESH
HumansMESH
Immunotherapy, AdoptiveMESH
Indium Radioisotopes/pharmacokineticsMESH
Macrophage ActivationMESH
Macrophages/metabolismMESH
Monocytes/immunologyMESH
Neoplasms/therapyMESH
Organometallic Compounds/pharmacokineticsMESH
Oxyquinoline/pharmacokineticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:06
Last Modified:14 Apr 2010 05:06
Item ID:14293
Owner Only: item control page
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