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Differential effects of cell adherence on LPS-stimulated cytokine production by human monocytes and macrophages

Krause, S. W. and Kreutz, M. and Andreesen, Reinhard (1996) Differential effects of cell adherence on LPS-stimulated cytokine production by human monocytes and macrophages. Immunobiology 196 (5), pp. 522-34.

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Abstract

It is well known that adherence of monocytes (MO) to extracellular matrix substrates or tissue culture plastic activates these cells and induces the expression of a multitude of genes. Especially, it was described, that MO are primed by cell adhesion to produce higher amounts of some cytokines, e.g. interleukin (IL)-8 and tumor necrosis factor alpha (TNF-alpha). In order to investigate ...

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Item Type:Article
Date:1996
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
9145330PubMed ID
Classification:
NotationType
Cell Adhesion/immunologyMESH
Cells, CulturedMESH
Cytokines/drug effectsMESH
Down-Regulation/immunologyMESH
Granulocyte Colony-Stimulating Factor/biosynthesisMESH
HumansMESH
Lipopolysaccharides/pharmacologyMESH
Macrophages/metabolismMESH
Monocytes/metabolismMESH
Salmonella/metabolismMESH
Tumor Necrosis Factor-alpha/biosynthesisMESH
Up-Regulation/immunologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:00
Last Modified:14 Apr 2010 05:00
Item ID:14301
Owner Only: item control page
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