Startseite UB

Effective biomodulation by leucovorin of high-dose infusion fluorouracil given as a weekly 24-hour infusion: results of a randomized trial in patients with advanced colorectal cancer

Köhne, C. H. and Schöffski, P. and Wilke, H. and Käufer, C. and Andreesen, Reinhard and Ohl, U. and Klaasen, U. and Westerhausen, M. and Hiddemann, W. and Schott, G. and Harstick, A. and Bade, J. and Horster, A. and Schubert, U. and Hecker, H. and Dörken, B. and Schmoll, H. J. (1998) Effective biomodulation by leucovorin of high-dose infusion fluorouracil given as a weekly 24-hour infusion: results of a randomized trial in patients with advanced colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 16 (2), pp. 418-26.

Full text not available from this repository.

at PubMed


Abstract

PURPOSE: To determine whether high-dose infusional fluorouracil (FU) is effectively modulated by leucovorin (LV), interferon (IFN) alpha-2b, or both when given to patients with metastatic colorectal cancer. PATIENTS AND METHODS: Patients (n = 236) with progressive, measurable disease were randomized to three groups and received FU 2,600 mg/m2 as a 24-hour continuous infusion (CI) weekly for 6 ...

plus


Export bibliographical data



Item Type:Article
Date:1998
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
10334556PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
Antimetabolites, Antineoplastic/adverse effectsMESH
Colorectal Neoplasms/pathologyMESH
Disease ProgressionMESH
Drug Administration ScheduleMESH
FemaleMESH
Fluorouracil/adverse effectsMESH
HumansMESH
Immunologic Factors/administration & dosageMESH
Infusions, IntravenousMESH
Interferon Alfa-2b/administration & dosageMESH
Leucovorin/administration & dosageMESH
MaleMESH
Middle AgedMESH
Prospective StudiesMESH
Survival RateMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:34
Last Modified:15 Apr 2010 05:34
Item ID:14324
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact