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Antibodies TC-12 ("unique") and TH-111 (CD96) characterize T-cell acute lymphoblastic leukemia and a subgroup of acute myeloid leukemia

Gramatzki, M. and Ludwig, W. D. and Burger, R. and Moos, P. and Rohwer, P. and Grünert, C. and Sendler, A. and Kalden, J. R. and Andreesen, Reinhard and Henschke, F. and Moldenhauer, G. (1998) Antibodies TC-12 ("unique") and TH-111 (CD96) characterize T-cell acute lymphoblastic leukemia and a subgroup of acute myeloid leukemia. Experimental hematology 26 (13), pp. 1209-14.

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Abstract

To extend the panel of monoclonal antibodies useful for immunophenotyping of acute leukemias, two new reagents, TC-12 and TH-111, were developed. TC-12 was found "unique," and TH-111 was assigned to the recently defined CD96 cluster. Both reagents show little reactivity with blood and bone marrow nucleated cells but define a major (TH-111: 78.3%) or an important (TC-12: 45.6%) subset of T-cell ...

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Item Type:Article
Date:1998
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
9845376PubMed ID
Classification:
NotationType
AnimalsMESH
Antibodies, MonoclonalMESH
Antibody SpecificityMESH
Antigens, CD/immunologyMESH
Antigens, Neoplasm/immunologyMESH
FemaleMESH
HumansMESH
Hybridomas/immunologyMESH
ImmunophenotypingMESH
Immunosorbent TechniquesMESH
Indicators and ReagentsMESH
Leukemia, Myeloid, Acute/immunologyMESH
Leukemia-Lymphoma, Adult T-Cell/immunologyMESH
MiceMESH
Mice, Inbred BALB CMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:34
Last Modified:15 Apr 2010 05:34
Item ID:14325
Owner Only: item control page
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